Can creatinine levels go up and down?
* Muscle mass: Creatinine is produced by the muscles, so people with more muscle mass will have higher creatinine levels.
* Kidney function: Creatinine is excreted by the kidneys, so people with kidney disease will have higher creatinine levels.
* Diet: Eating a diet that is high in protein can increase creatinine levels.
* Dehydration: Dehydration can increase creatinine levels.
* Certain medications: Some medications, such as cimetidine and trimethoprim, can increase creatinine levels.
If you have any concerns about your creatinine levels, talk to your doctor.