Do you need to retake the shot after are finished with antibiotics?

In most cases, you do not need to retake a vaccination after finishing antibiotics. Antibiotics are used to treat bacterial infections, while vaccinations are used to protect against viral infections. Antibiotics do not interfere with the effectiveness of vaccines, and in fact, some antibiotics can even help to boost the immune response to certain vaccines. However, if you have a weakened immune system, your doctor may recommend that you retake the vaccine after completing a course of antibiotics.