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Passion Flower Side Effects

Dried passion flower is traditionally used for gastrointestinal problems and as a sedative to treat insomnia. According to the National Institutes of Health (NIH), evidence indicates the herb may have a calming action similar to benzodiazepines, which are depressants. The NIH considers passion flower a safe herb with few side effects.

  1. Most Likely Effects

    • Passion flower causes drowsiness and sedation, as well as dizziness and slower thinking. Other side effects include rapid heartbeat, nausea and vomiting.

    Increased Bleeding

    • The herb may increase the risk of bleeding, particularly when taken with anticoagulants, such as warfarin or heparin, and anti-inflammatory drugs such as ibuprofen and aspirin.

    Drowsiness-Causing Drugs

    • Using passion flower with other drugs that cause drowsiness can increase this effect. Examples include alcohol, benzodiazepines, barbiturates, narcotics and some antidepressants.

    Other Drug Interactions

    • Passion flower may increase the effects of monoamine oxidase inhibitory (MAOI) drugs, and increase the risk of low-blood pressure when taken with tricyclic antidepressants and selective serotonin reuptake inhibitors (SSRIs).

    Allergic Reaction

    • Rarely, some people may have an allergic reaction to passion flower. Signs of an allergic reaction include rash or hives, itching, dizziness, swelling and difficulty breathing.

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