Grape Seed Extract Effects

Grape seed extract (GSE) a popular dietary supplement used for its claimed health benefits. In laboratory studies, it has been found that the grape seed is a source of antioxidants. Antioxidants are important natural agents that help to fight the negative effects of environmental free radicals that are known to cause skin damage and aging. The antioxidants in grape seeds help to prevent cell function damage that can be caused by these free radicals.

Identification

• Grape seed extract is derived from the grape seed. The scientific name for grapes is Vitis vinifera, and it is a deciduous plant that grows in full sun. The plant's fruits are edible, and it is especially enjoyed, medicinally, for its seeds and skin. Eating the grapes with the seeds may improve the antioxidant effects.

Effects

• Grape seed extract may have a beneficial effect on the circulatory system. It has been used to increase heart health and improve circulation, and it may have some benefit against hypertension and high cholesterol levels. Grape seed extract may also help to treat atherosclerosis.

Benefits

• Grape seed extract is said to have an effect on cancer and preventing its occurrence, as well as complications associated with diabetes, such as with vision and the nerves. It may also help to reduce swelling, and is used to help heal wounds.

Expert Insight

• The National Cancer institute (NCI) has conducted studies on the effects of grape seed extract on cancer, particularly of the prostate and breast. The University of Kentucky conducted laboratory studies that demonstrated the positive effect of grape seed extract on leukemia cells. Grape seed extract sped up the cellular suicide of these cancer cells, causing 76 percent of the leukemia cells to die by apoptosis (programmed cell death). Further studies will have to examine grape seed extract's effect on these cancerous cells within the body.

Warning

• Side effects associated with taking grape seed extract include headache, nausea, dizziness and scalp irritation. However, grape seed extract is usually well tolerated when taken in oral form over an extended period of time. Complete drug interactions are not yet available, and as always, a doctor should be consulted about the use of grape seed extract, both alone and in conjunction with other medications.