Milk Thistle Seed Side Effects

People have been using this Mediterranean herb for more than 2,000 years for the protection and healing of the liver. The primary active ingredient in milk thistle is silybin. The seeds can be eaten in the whole-seed form or in an extract, while others prefer a whole plant capsule for a more balanced and standardized dosage.
  1. Studies

    • According to a 2007 article published by the National Institutes of Health, European studies seem to support using milk thistle seeds to protect the liver from damage. Current studies have been conducted for use of silybin in cancer treatment but as of yet, the results are inconclusive. All studies report some sort of side-effects, but most are mild.

    Allergic Reactions

    • People who are allergic to composites, like artichokes, ragweed and daisies, may have an allergic reaction to silybin in milk thistle seeds. Usually this is limited to skin rashes, but there have also been reports of anaphalixis which can be fatal if untreated.

    Diarrhea

    • According to the University of Maryland, a 2000 clinical trial using milk thistle seeds, there have been reports of digestive problems including bloating, gas and Although these side effects are usually not harmful, they can be uncomfortable and diarrhea should always be taken seriously because it can cause dehydration.

    Long-term Side Effects

    • Anecdotal claims throughout the century have not shown any long-term side effects of using milk thistle seed. Currently, studies have shown that milk thistle seeds are safe for most people when taken for up to 41 months. However, if you plan on taking it for a longer period of time, consult with your doctor about the safety and possible interactions with other medications.

    At Risk Groups

    • Because there have been no studies on the use of mild thistle seeds for children and pregnant and nursing women, the use of mild thistle seeds should be avoided. Anyone who suspects he may have hepatitis or liver problems, should see a qualified doctor before using milk thistle seeds. These are serious conditions and may be fatal without proper care.

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