What is the pathophysiology of MRSA?

Pathophysiology of MRSA

MRSA is a type of Staphylococcus aureus (S. aureus) bacteria that is resistant to methicillin, a type of antibiotic. It is a major cause of healthcare-associated infections, and it can also cause infections in the community.

MRSA produces a protein called PBP2a, which binds to methicillin and other beta-lactam antibiotics and prevents them from working. This makes MRSA resistant to these antibiotics.

MRSA can cause a variety of infections, including:

* Skin and soft tissue infections, such as abscesses, cellulitis, and impetigo

* Respiratory tract infections, such as pneumonia and bronchitis

* Urinary tract infections

* Bloodstream infections

* Bone and joint infections

MRSA can be spread through contact with an infected person or by touching contaminated surfaces. It can also be spread through the air in droplets from coughs or sneezes.

MRSA infections can be treated with antibiotics that are effective against MRSA, such as vancomycin, daptomycin, or linezolid. However, MRSA infections can be difficult to treat, and they can sometimes be fatal.

Risk factors for MRSA infection

The following factors increase the risk of MRSA infection:

* Being hospitalized or in a long-term care facility

* Having a weakened immune system

* Having a history of MRSA infection

* Being in contact with someone who has MRSA

Preventing MRSA infection

The following steps can help to prevent MRSA infection:

* Wash your hands frequently with soap and water, especially after coughing, sneezing, or touching public surfaces.

* Avoid touching your face with unwashed hands.

* Cover any open wounds with a clean bandage.

* Keep your home and workplace clean.

* Avoid contact with people who have MRSA infection.

If you think you might have a MRSA infection, see your doctor right away.