Can you take opana and suboxone together?

No, it is dangerous to combine Opana and Suboxone together.

Opana is a potent opioid, which means that it has a high risk of dependence. Mixing Opana with Suboxone creates the risk of respiratory depression, hypotension, coma, and overdose. Both drugs should not be taken concurrently, and Suboxone should only be used one week after discontinuation of Opana.