Does niacin deficiency causes neural tube defects?

Yes, niacin deficiency can cause neural tube defects.

Neural tube defects (NTDs) are a group of birth defects that affect the brain and spinal cord. They occur when the neural tube, which is the precursor to the brain and spinal cord, does not close properly during fetal development.

Niacin, also known as vitamin B3, is an essential nutrient that is involved in a number of bodily functions, including energy production, metabolism, and nerve function. Niacin deficiency is a rare condition, but it can occur in people who do not eat a balanced diet or who have certain medical conditions.

Niacin deficiency during pregnancy has been linked to an increased risk of NTDs. This is because niacin is essential for the proper development of the neural tube. When niacin levels are low, the neural tube may not close properly, leading to an NTD.

Some studies have shown that taking niacin supplements before and during pregnancy can help to reduce the risk of NTDs. However, it is important to note that niacin supplements should only be taken under the supervision of a doctor. Too much niacin can be harmful, so it is important to follow the recommended dosage.

If you are pregnant or planning to become pregnant, it is important to eat a healthy diet that includes foods rich in niacin, such as lean meat, poultry, fish, legumes, nuts, and seeds. You may also want to consider taking a prenatal vitamin that contains niacin.