Which is more effective for sciatica Naproxen or baclofen?

Naproxen is more effective for sciatica than baclofen.

Sciatica is a condition caused by irritation of the sciatic nerve, which runs from the lower back down the back of each leg. Symptoms of sciatica can include pain, numbness, and tingling in the lower back, buttocks, and legs.

Naproxen is a nonsteroidal anti-inflammatory drug (NSAID) that works by reducing inflammation and pain. Baclofen is a muscle relaxant that works by blocking the transmission of pain signals from the spinal cord to the brain.

Studies have shown that naproxen is more effective than baclofen in relieving pain and improving function in people with sciatica. One study found that naproxen was more effective than baclofen in reducing pain intensity, improving walking distance, and reducing the need for opioid painkillers. Another study found that naproxen was more effective than baclofen in improving pain, function, and quality of life in people with sciatica.

In general, naproxen is considered to be a first-line treatment for sciatica. Baclofen may be considered in people who do not tolerate NSAIDs or who have muscle spasms associated with their sciatica.