What Causes Priapism?

Priapism is a medical condition characterized by an persistent, often painful erection of the penis that is unrelated to sexual arousal or stimulation. It is caused by a combination of factors and can be classified into two main types: ischemic and non-ischemic priapism.

1. Ischemic Priapism:

- Sickle Cell Anemia: A condition where abnormal sickle-shaped red blood cells can block small blood vessels, leading to impaired blood flow out of the penis.

- Trauma or injury to the penis or perineum: This can damage the blood vessels and nerves, causing an interruption in blood flow.

- Medications: Certain medications, including antidepressants, anticoagulants, and antihistamines, have been linked to ischemic priapism.

- Blood disorders: Conditions such as leukemia and multiple myeloma can increase the risk of priapism.

2. Non-Ischemic Priapism:

- Medications: Some medications, such as certain erectile dysfunction drugs (e.g., sildenafil, tadalafil) can cause prolonged erections.

- Neurological conditions: Damage to the nerves that control penile erection can lead to persistent engorgement.

- Spinal cord injuries: Injuries affecting the lower spinal cord can disrupt nerve signals involved in controlling erectile function.

- Drug use: Illegal drugs, such as cocaine and amphetamines, can also cause priapism.

It's important to seek immediate medical attention if you experience priapism, especially if it lasts more than 4 hours. Prompt treatment can prevent long-term complications such as erectile dysfunction. The underlying cause of priapism will determine the appropriate treatment options.