What is uncinate hypertrophy?

Uncinate hypertrophy refers to an overgrowth of tissue in the uncinate process, which is a small, hook-shaped structure located in the medial temporal lobe of the brain. It involves abnormal enlargement and protrusion of the uncinate fasciculus, a white matter tract that connects the amygdala and hippocampus to the prefrontal cortex. This condition is associated with temporal lobe epilepsy, particularly mesial temporal lobe epilepsy, and has been implicated in memory problems and cognitive impairments experienced by individuals with epilepsy.