| | Alternative Medicine | Trepanation What does the medical terminology combining form perineo- mean? The medical terminology combining form perine- means "perineum." The perineum is the region of the body between the anus and the genitals. Trepanation - Related Articles What Are the Causes of Gliomas? History of Louisiana Offshore Drilling How to Handle Allergies What Are the Causes of Main Artery Enlargement? How To Relieve TMJ Symptoms Multipolar Disorder What is the first treatment for thiamine deficiency?