What could explain red itchy blotches on ankles the size of quarters?

- Insect bites or stings (such as from mosquitoes, fleas, or chiggers)

- Allergic reactions (e.g. to contact with allergens such as poison ivy, poison oak, or certain chemicals)

- Skin infections (such as cellulitis or impetigo)

- Atopic dermatitis (a type of eczema)

- Drug reactions