What coditions have a large tongue?

Several medical conditions are associated with having a large tongue:

1. Acromegaly: Acromegaly is a hormonal disorder caused by excessive growth hormone production. One of the physical features of acromegaly is enlargement of the bones and soft tissues, including the tongue.

2. Amyloidosis: Amyloidosis is a rare condition characterized by the abnormal deposition of amyloid proteins in various tissues and organs. When amyloid deposits accumulate in the tongue, it can lead to enlargement and thickening, giving it a firm and rigid texture.

3. Beckwith-Wiedemann Syndrome: Beckwith-Wiedemann Syndrome is a genetic disorder involving overgrowth of certain body parts. Children with this syndrome often have a large tongue from birth, also known as macroglossia.

4. Down Syndrome: Down Syndrome is a genetic condition caused by an extra copy of chromosome 21. Individuals with Down Syndrome may have distinct physical features, including a large tongue that often protrudes from the mouth.

5. Hypothyroidism: Hypothyroidism is a condition where the thyroid gland does not produce enough thyroid hormone. In some cases, it can cause swelling of the tongue, leading to an enlarged appearance.

6. Idiopathic Macroglossia: In some cases, an enlarged tongue may not be associated with any underlying medical condition and is referred to as idiopathic macroglossia. The cause of the tongue enlargement remains unknown in such cases.

7. Myxedema: Myxedema is a severe form of hypothyroidism. It can cause significant swelling of the face, hands, feet, and tongue, resulting in an enlarged appearance.

It's important to note that the presence of a large tongue should be evaluated by a healthcare professional. They can determine the underlying cause and recommend appropriate treatment or management if necessary.