Is there any chemo better than lapatanib for metastatic cancer?

There may be other chemotherapies that are better than lapatanib for metastatic cancer, depending on the specific type and stage of cancer. Some alternative chemotherapies that may be used in combination with or instead of lapatanib include:

Trastuzumab: A monoclonal antibody that blocks the HER2 receptor, typically used in combination with chemotherapy for HER2-positive breast cancer.

Pertuzumab: Another monoclonal antibody that targets HER2, often used in combination with trastuzumab and docetaxel for HER2-positive breast cancer.

Docetaxel: A taxane chemotherapy drug that inhibits cell division, commonly used for metastatic breast cancer.

Paclitaxel: Another taxane chemotherapy drug similar to docetaxel, also used for metastatic breast cancer.

5-fluorouracil (5-FU): A fluoropyrimidine chemotherapy drug that interferes with DNA synthesis and is often used in combination with other agents for various types of cancer.

Capecitabine: An oral form of 5-FU that is converted into 5-FU after absorption in the body, used for certain cancers including colorectal cancer and breast cancer.

Gemcitabine: A nucleoside analog chemotherapy drug that interferes with DNA synthesis, commonly used for pancreatic cancer and other types of cancer.

Cisplatin: A platinum-based chemotherapy drug that damages DNA and inhibits cell division, used for various types of cancer including lung cancer, testicular cancer, and certain head and neck cancers.

These are just a few examples, and the selection of the most appropriate chemotherapy regimen for metastatic cancer depends on several factors such as the type and stage of cancer, overall health, and previous treatments. It's important to consult with a medical oncologist or cancer specialist to determine the best course of treatment.