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What Are the Causes of CLL?

Chronic lymphocytic leukemia, or CLL, is a cancer that occurs in a patient's bone marrow and blood. CLL affects white blood cells known as the lymphocytes. This disease often progresses at a slower pace than other types of leukemia.
  1. Genetic Mutation

    • According to the Mayo Clinic, CLL occurs when genetic mutations in the bone marrow cause abnormal lymphocytes to be created that are not effective at fighting infections.

    Family History

    • Individuals with a family history of CLL may be at a greater risk of developing the disease.

    Chemicals

    • Exposure to Agent Orange and other insecticides or herbicides increases the likelihood of developing CLL.

    Demographics

    • Men and people over the age of 50 have a higher risk of getting chronic lymphocytic leukemia. Whites have a higher likelihood of developing CLL than people of other races.

    Symptoms

    • CLL may develop without symptoms or it may cause painless enlarged lymph nodes, fever and fatigue. Frequent infections, night sweats and weight loss may also occur.

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