Is sickle cell anemia a disease from mutation?

Yes, sickle cell anemia is a genetic disorder caused by a mutation in the beta-globin gene. This mutation results in the production of a defective form of beta-globin, which is a protein that is part of the hemoglobin molecule. Hemoglobin is responsible for carrying oxygen throughout the body. The defective beta-globin causes the red blood cells to become sickle-shaped, which can lead to a number of health problems, including pain, fatigue, and organ damage.