What does bisphosphanates mean?

Bisphosphonates are a class of drugs used to treat a variety of bone diseases. They work by slowing down the breakdown of bone tissue, which can help to increase bone density and reduce the risk of fractures. Bisphosphonates are typically used to treat osteoporosis, a condition that causes bones to become weak and brittle. They can also be used to treat other bone diseases, such as Paget's disease and osteogenesis imperfecta.

Bisphosphonates are available in both oral and intravenous forms. The type of bisphosphonate that is used and the dosage will depend on the individual's condition. Bisphosphonates are generally well-tolerated, but they can cause side effects such as nausea, vomiting, diarrhea, and constipation. In rare cases, bisphosphonates can cause serious side effects such as osteonecrosis of the jaw (ONJ) and atypical femoral fractures.

ONJ is a condition that occurs when the jawbone becomes exposed due to a loss of bone tissue. ONJ is a rare side effect of bisphosphonates, but it can be serious. Atypical femoral fractures are also a rare side effect of bisphosphonates. Atypical femoral fractures are fractures that occur in the thigh bone (femur) that are not caused by a major trauma.

The risk of developing ONJ or atypical femoral fractures is increased with long-term use of bisphosphonates. However, the risk of these side effects is still relatively low. Bisphosphonates are an effective treatment for a variety of bone diseases, and they are generally well-tolerated.

Here are some of the most common bisphosphonates:

* Alendronate (Fosamax)

* Risedronate (Actonel)

* Ibandronate (Boniva)

* Zoledronic acid (Reclast)

* Pamidronate (Aredia)

These drugs are typically taken once a week or once a month. They can be taken orally or intravenously.

Bisphosphonates are effective in preventing and treating osteoporosis. They can also be used to treat other bone diseases, such as Paget's disease and osteogenesis imperfecta.