Do sickle cells have a nucleus?

Yes, sickle cells have a nucleus. Sickle cells are red blood cells that have a defective form of hemoglobin, which is a protein responsible for carrying oxygen in the blood. Sickle cells are shaped like sickles or crescent moons, and they can become stuck in small blood vessels, blocking the flow of blood and oxygen to tissues and organs. Although sickle cells have an abnormal shape, they still contain all of the usual components of a red blood cell, including a nucleus. The nucleus contains the cell's DNA, which is the genetic material that controls the cell's functions.