Is liver is able to regenerate even after 50 percent of its original mass lost?

The liver has a remarkable ability to regenerate itself even after losing a significant portion of its mass. In fact, the liver can regenerate itself even after losing up to 75% of its original mass. This process of regeneration is essential for the liver to maintain its function and overall health.

When a portion of the liver is damaged or removed, the remaining liver cells begin to divide and multiply rapidly in order to replace the lost tissue. This process is controlled by a variety of growth factors and hormones, and it can take several weeks or months for the liver to fully regenerate.

The liver's ability to regenerate is essential for its survival and function. The liver is responsible for a wide range of vital functions, including detoxification of harmful substances, production of proteins and bile, and storage of glycogen and other nutrients. Without the ability to regenerate, the liver would not be able to perform these functions and the body would eventually succumb to liver failure.

The liver's regenerative capacity is also important for the success of liver transplantation. In a liver transplant, a healthy liver is transplanted into a person whose liver has failed. The transplanted liver then begins to regenerate and eventually takes over the functions of the failed liver.