Is neuroendocrine cancer that has spread to liver treatable?
Neuroendocrine cancer that has spread to the liver is often a more advanced stage of the disease and may be more challenging to treat compared to earlier stages. However, there are still a number of treatment options available, and the prognosis can vary depending on several factors, including the type and location of the primary tumor, the extent of liver involvement, and the patient's overall health.
Treatment for neuroendocrine cancer that has spread to the liver may involve a combination of different therapies, including:
1. Somatostatin Analogues: These medications, such as octreotide and lanreotide, can control hormone production and help manage symptoms associated with neuroendocrine tumors.
2. Targeted Therapy: Drugs like everolimus and sunitinib may be used to inhibit the growth and spread of neuroendocrine tumors by blocking specific molecular pathways.
3. Peptide Receptor Radionuclide Therapy (PRRT): This treatment uses radioactive substances that bind to receptors commonly found on neuroendocrine cells. When the radioactive substance is administered, it delivers targeted radiation therapy to the neuroendocrine tumors.
4. Chemotherapy: Conventional chemotherapy drugs may be used to destroy or slow the growth of neuroendocrine tumors.
5. Radiation Therapy: External beam radiation therapy or radiofrequency ablation may be used to target and destroy liver metastases.
6. Surgical Resection: In some cases, surgery may be an option to remove liver metastases if they are localized and considered resectable.
7. Liver-Directed Therapies: These therapies, such as transarterial chemoembolization (TACE) or radioembolization, aim to deliver concentrated treatment to the liver while minimizing systemic side effects.
8. Clinical Trials: Enrolling in clinical trials may offer access to experimental treatments and cutting-edge therapies not yet widely available.
The specific treatment plan will depend on the individual patient's situation and should be determined in consultation with a healthcare team experienced in treating neuroendocrine cancer. The goals of treatment may include controlling symptoms, slowing the progression of the disease, and improving overall quality of life.