How EGFR-Positive Lung Cancer Is Treated

Treatment for EGFR-positive lung cancer may include:

Surgery: If the cancer is localized and has not spread to other parts of the body, surgery may be an option. The type of surgery will depend on the location and size of the tumor.

Targeted therapy: Targeted therapy drugs block the action of the EGFR protein, which helps to slow or stop the growth of cancer cells. Several targeted therapy drugs are approved for the treatment of EGFR-positive lung cancer, including erlotinib (Tarceva), gefitinib (Iressa), and osimertinib (Tagrisso).

Chemotherapy: Chemotherapy drugs kill cancer cells throughout the body. Chemotherapy may be used before surgery to shrink the tumor, after surgery to kill any remaining cancer cells, or in combination with targeted therapy.

Immunotherapy: Immunotherapy drugs help the immune system to recognize and attack cancer cells. Immunotherapy may be an option for people with advanced EGFR-positive lung cancer who have not responded to other treatments.

Radiation therapy: Radiation therapy uses high-energy X-rays or other forms of radiation to kill cancer cells. Radiation therapy may be used before surgery, after surgery, or in combination with other treatments.

The best treatment option for a person with EGFR-positive lung cancer will depend on the individual's overall health, the stage of the cancer, and the type of EGFR mutation. A doctor can help to develop a treatment plan that is right for you.