What can cause scarring on the upper lobe of lung in a non-smoker?

1. Sarcoidosis:

Sarcoidosis is an inflammatory disease that can affect multiple organs, including the lungs. It is characterized by the formation of granulomas, which are small collections of inflammatory cells. In some cases, sarcoidosis can cause scarring in the upper lobes of the lungs, leading to shortness of breath, cough, and fatigue.

2. Interstitial Lung Disease (ILD):

ILD is a group of lung diseases that involve inflammation and scarring of the lung tissue. Idiopathic pulmonary fibrosis (IPF) is a common type of ILD that can cause scarring in the upper lobes of the lungs. IPF is a progressive disease, meaning it worsens over time, leading to shortness of breath, cough, and fatigue.

3. Chronic Infections:

Certain chronic infections, such as tuberculosis (TB), fungal infections, and nontuberculous mycobacterial infections, can cause scarring in the upper lobes of the lungs. These infections can damage the lung tissue, leading to the formation of scar tissue. Symptoms may include cough, shortness of breath, fever, and weight loss.

4. Radiation Therapy:

Radiation therapy used for the treatment of cancer in the chest area can also lead to scarring in the upper lobes of the lungs. The radiation can damage the lung tissue, causing inflammation and the formation of scar tissue. Symptoms may include cough, shortness of breath, and chest pain.

5. Autoimmune Diseases:

Certain autoimmune diseases, such as rheumatoid arthritis and systemic lupus erythematosus (SLE), can cause inflammation in the lungs and lead to scarring. These diseases can affect the upper lobes of the lungs, causing shortness of breath, cough, and fatigue.

6. Environmental Exposures:

Exposure to certain environmental toxins and pollutants, such as asbestos, silica dust, and certain chemicals, can cause scarring in the upper lobes of the lungs. These exposures can damage the lung tissue and lead to inflammation and fibrosis. Symptoms may include cough, shortness of breath, and wheezing.

7. Drug Reactions:

Some medications, such as methotrexate, amiodarone, and bleomycin, can cause lung damage leading to scarring. These medications can cause inflammation in the lungs and damage to the lung tissue, resulting in the formation of scar tissue. Symptoms may include cough, shortness of breath, and fatigue.

It's important to consult a healthcare professional for a proper diagnosis and evaluation of any lung scarring.