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At how much conc o-dianicidine is carcinogenic?
The carcinogenicity threshold for o-dianisidine is highly dependent on the route of exposure, the species, and the individual's susceptibility. Limited studies on humans suggest a potential risk of cancer, particularly bladder cancer, at occupational exposure levels. However, the exact concentration at which o-dianisidine becomes carcinogenic in humans is not precisely established.
Animal studies have shown varying results depending on the species and the experimental conditions. In general, chronic exposure to o-dianisidine at relatively high concentrations has been associated with an increased risk of bladder, lung, and mammary gland tumors in certain animal models.
In occupational settings, regulations and guidelines are often in place to limit exposure to o-dianisidine and minimize potential health risks. These regulations aim to keep the exposure concentrations well below the levels known to cause adverse health effects.
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