What Is Exocrine Pancreatic Insufficiency?

Exocrine pancreatic insufficiency (EPI) is a condition in which the pancreas does not produce enough digestive enzymes. This can lead to malabsorption, or the inability to absorb nutrients from food.

EPI can be caused by a number of factors, including:

* Chronic pancreatitis: This is a long-term inflammation of the pancreas.

* Pancreatic cancer: This is a type of cancer that starts in the pancreas.

* Cystic fibrosis: This is a genetic disorder that affects the lungs and other organs, including the pancreas.

* Diabetes: This is a chronic disease that affects the body's ability to produce or use insulin.

* Certain medications: Some medications, such as proton pump inhibitors (PPIs) and antacids, can interfere with the absorption of digestive enzymes.

* Surgery: Surgery to remove the pancreas or part of the pancreas can lead to EPI.

EPI can cause a number of symptoms, including:

* Weight loss

* Diarrhea

* Fatty stools

* Abdominal pain

* Bloating

* Gas

* Fatigue

* Vitamin and mineral deficiencies

EPI is diagnosed with a combination of blood tests, stool tests, and imaging tests. Treatment for EPI typically involves taking pancreatic enzyme supplements with meals. These supplements help the body to digest food and absorb nutrients.

EPI is a serious condition, but it can be managed with treatment. By taking pancreatic enzyme supplements, people with EPI can live full and healthy lives.