Risk of Metastasis in Prostate Cancer

Prostate cancer, like any other form of cancer, can metastasize (spread to other parts of the body). However, according to the National Cancer Institute, if you have a low-grade prostate cancer it will probably grow and metastasize slowly.

Gleason Scores

• Prostate cancers are given a Gleason Score. Gleason Scores run from 2 to 10 and indicate whether the cancer is a slow-growing variety or an aggressive type that will metastasize quickly.

Low Grade

• A Gleason Score of 2 to 4 is given to low-grade cancers. These cancers tend to develop and spread slowly.

Intermediate Grade

• Cancers in the 5 to 7 range are considered intermediate grade. According to the Merck Manual, scores of 6 and 7 are most common.

High Grade

• A Gleason Score of 8 to 10 is assigned to high-grade prostate cancers. These tumors can spread rapidly.

Active Surveillance

• Older men who have a low Gleason Score and no troubling symptoms may be advised to take an "active surveillance" approach. Some doctors choose the option of regular, follow-up testing because surgery and radiation have not been shown to extend the lives of older patients.

Caution

• The Merck Manual stresses active surveillance may not be appropriate for younger men because even a slow-growing cancer could cause problems in the future.