Has anyone ever been born without a prostate?

Yes, individuals can be born without a prostate, although it is a rare occurrence. This condition is known as congenital prostatic agenesis or prostatic aplasia. It occurs due to abnormal development during embryonic growth, resulting in the absence of the prostate gland.

Congenital prostatic agenesis is often associated with other medical conditions, such as imperforate anus, hypospadias (a birth defect in which the opening of the urethra is not at the tip of the penis), and prune belly syndrome (a rare condition characterized by a wrinkled and loose abdomen).

In affected individuals, the absence of the prostate gland can lead to various health implications, including infertility, decreased libido, and sexual dysfunction. Additionally, the surrounding structures in the pelvic region may be affected, including the seminal vesicles and associated ducts.

To confirm the absence of the prostate gland, diagnostic tests such as ultrasound imaging, magnetic resonance imaging (MRI), or a biopsy may be performed. Treatment options for individuals with congenital prostatic agenesis may include hormone replacement therapy and addressing any associated conditions or symptoms.

While rare, congenital prostatic agenesis highlights the importance of normal embryonic development and the role of the prostate gland in male reproductive health. However, it's worth noting that medical knowledge and technological advancements continue to contribute to the understanding and management of such rare conditions.