Advanced Melanoma: What to Expect

Advanced melanoma, also known as metastatic melanoma, refers to the stage of melanoma when the cancer has spread beyond the primary tumor site to other parts of the body. Depending on the location and extent of the metastases, the signs and symptoms of advanced melanoma can vary. Here are some things you may expect:

1. Skin changes: Melanoma can spread to other areas of the skin, leading to the development of new moles or changes in existing moles. These changes may include an increase in size, changes in shape or color, and the development of irregular borders.

2. Lymph node involvement: Melanoma often spreads to nearby lymph nodes, which can cause swelling or enlargement of the lymph nodes. This may be felt as a lump or swelling under the skin in areas such as the neck, armpits, or groin.

3. Lung metastases: Melanoma commonly metastasizes to the lungs. Symptoms of lung metastases may include shortness of breath, coughing, chest pain, or fatigue.

4. Liver metastases: Metastasis to the liver can cause abdominal pain or discomfort, nausea, vomiting, or a loss of appetite.

5. Bone metastases: Melanoma that spreads to the bones can cause pain, tenderness, or fractures in the affected areas. Bone pain may be persistent or worsen with activity.

6. Brain metastases: Melanoma can rarely metastasize to the brain, leading to symptoms such as headaches, seizures, vision changes, memory problems, or difficulty with balance and coordination.

7. General symptoms: Advanced melanoma can cause a range of general symptoms, including fatigue, weight loss, loss of appetite, night sweats, or a decreased ability to tolerate physical activity.

It's important to note that not all individuals with advanced melanoma will experience all of these symptoms. The specific symptoms experienced will depend on the location and extent of the metastases, as well as individual variations. If you have been diagnosed with advanced melanoma, it is essential to work closely with your healthcare team to manage your symptoms and receive appropriate treatment.