| | Cancer | Skin Cancer What is the origin of melanoma? The main type of melanoma arises from the pigment cells (melanocytes) in the skin. The melanocytes are most commonly found in the epidermis, the outermost skin layer. Skin Cancer - Related Articles What Are Fruits in the Food Groups? Where does lymph come from? Can the body fight human rhinovirus infection? How many diabetes are there? What Is Resveratrol Extract? How much do anesteciologist make? Can you have a hamburger with diverticulitis?