What are keratinocytes?

Keratinocytes are the most abundant cells in the epidermis, the outermost layer of the skin. They produce keratin, a protein that gives skin its strength and flexibility. Keratinocytes also help to protect the skin from damage caused by UV radiation, heat, and chemicals.

Keratinocytes are constantly dividing and moving towards the surface of the skin. As they move, they become filled with keratin and eventually die. The dead cells are then shed from the skin's surface. This process of cell division and shedding is called desquamation.

Desquamation is essential for maintaining healthy skin. It helps to remove dead cells and debris from the skin's surface, and it allows new cells to come to the surface. Desquamation also helps to protect the skin from infection.

Keratinocytes are also involved in the production of melanin, the pigment that gives skin its color. Melanin helps to protect the skin from damage caused by UV radiation.

Keratinocytes are essential for the health and function of the skin. They play a role in a variety of processes, including:

* Protection from damage

* Desquamation

* Production of melanin

Keratinocyte disorders can lead to a variety of skin problems, including:

* Psoriasis

* Eczema

* Ichthyosis

* Skin cancer

By understanding the role of keratinocytes in the skin, we can better understand and treat these disorders.