Does syphilis show up in routine blood test?

No, syphilis will not show up in routine blood tests, such as a complete blood count or a comprehensive metabolic panel. Blood tests for syphilis focus on checking for the presence of antibodies against the causative bacterium, Treponema pallidum. Two common tests used for syphilis detection are the rapid plasma reagin (RPR) test and the fluorescent treponemal antibody absorption (FTA-ABS) test. The RPR test provides a preliminary screening for syphilis, while the FTA-ABS test is used to confirm the diagnosis of syphilis. Syphilis testing often involves specific serological tests or specialized techniques designed to detect syphilis antibodies or identify the infecting pathogen directly.