What to Expect From CLL Treatment

The treatment for chronic lymphocytic leukemia (CLL) depends on the stage of the disease and the patient's overall health. The goal of treatment is to relieve symptoms, improve quality of life, and prolong survival.

Watch and wait

In the early stages of CLL, treatment may not be necessary. Your doctor may recommend a "watch and wait" approach, which means monitoring your condition closely for any signs of progression.

Targeted therapy

Targeted therapy is a type of treatment that uses drugs to attack specific proteins or molecules that are involved in the growth and survival of cancer cells. These drugs can be taken orally or given intravenously (IV). Some common targeted therapies used for CLL include:

* Ibrutinib (Imbruvica)

* Venetoclax (Venclexta)

* Idelalisib (Zydelig)

* Acalabrutinib (Calquence)

Chemotherapy

Chemotherapy is a type of treatment that uses drugs to kill cancer cells. Chemo drugs can be given orally or IV. Some common chemotherapy drugs used for CLL include:

* Fludarabine

* Cyclophosphamide

* Doxorubicin

* Bendamustine

Radiation therapy

Radiation therapy uses high-energy X-rays or other forms of radiation to kill cancer cells. Radiation therapy may be used to treat CLL that has spread to the lymph nodes or other organs.

Stem cell transplant

A stem cell transplant is a procedure that involves replacing damaged or diseased bone marrow with healthy stem cells. Stem cell transplants may be used to treat CLL that has not responded to other treatments.

Supportive care

Supportive care measures can help to relieve symptoms and improve quality of life during CLL treatment. These measures may include:

* Blood transfusions

* Antibiotics

* Antifungal medications

* Pain relievers

* Anti-nausea medications

* Counseling

Side effects of treatment

The side effects of CLL treatment can vary depending on the type of treatment you receive. Some common side effects include:

* Fatigue

* Nausea

* Vomiting

* Diarrhea

* Constipation

* Mouth sores

* Skin rash

* Hair loss

* Weight loss

* Increased risk of infection

* Increased risk of bleeding

Talk to your doctor

If you are considering treatment for CLL, talk to your doctor about the potential risks and benefits of each treatment option. Your doctor can help you choose the best treatment plan for your individual needs.