What is the best non-stimulant ADHD medication?

The best non-stimulant medication for ADHD depends on the individual case and what works best for them. Some commonly prescribed non-stimulant ADHD medications include:

1. Guanfacine (Intuniv, Tenex): Guanfacine belongs to a class of drugs known as central alpha-2A agonists. It works by increasing the levels of certain neurotransmitters in the brain, such as norepinephrine, and may improve attention and behavior.

2. Clonidine (Kapvay): Clonidine is another central alpha-2A agonist similar to guanfacine. It can be used alone or in combination with stimulants and has shown effectiveness in reducing hyperactivity and impulsivity.

3. Atomoxetine (Strattera): Atomoxetine is a selective noradrenaline reuptake inhibitor (SNRI) that works by increasing the levels of norepinephrine in the brain. It can improve attention and reduce hyperactivity and impulsivity.

4. Tricyclic antidepressants (TCAs): Some TCAs, such as desipramine (Norpramin) and nortriptyline (Pamelor), have been used off-label to treat ADHD. They may help improve attention and behavior by increasing the levels of certain neurotransmitters in the brain, such as norepinephrine and serotonin.

5. Bupropion (Wellbutrin): Bupropion, which is primarily prescribed as an antidepressant, has shown some effectiveness in treating ADHD. It is believed to work by increasing the levels of dopamine and norepinephrine in the brain.

It's important to note that the exact choice of non-stimulant ADHD medication should be made in consultation with a healthcare professional who has experience in treating ADHD. They will consider the individual patient's specific symptoms, medical history, and response to previous treatments when determining the best course of medication.