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Medications Used for ADHD Antihypertensives

Attention Deficit Hyperactivity Disorder (ADHD) is a condition characterized by difficulties with concentration, inattentiveness, hyperactivity and impulsivity. Antihypertensives may help treat symptoms of ADHD.

  1. Use

    • Antihypertensives are not FDA-approved for treating ADHD. Two antihypertensives, clonidine and guanfacine, appear to be most effective at treating symptoms of hyperactivity and impulsivity and less effective at improving attention.

    Function

    • Clonidine and guanfacine affect norepinephrine levels in the brain, leading to calming and sedating effects. This helps improve symptoms of ADHD.

    Interactions

    • Caution is advised when taking antihypertensives with benzodiazepines, barbituates and other CNS depressants, since they may significantly increase the depressant effect of these medications. Alcohol should be avoided when taking antihypertensives.

    Side Effects

    • Common side effects of clonidine and guanfacine include dry mouth, drowsiness, weakness, headache, nausea, vomiting and muscle and joint pain.

    Tic Disorders

    • According to researchers at the Yale Child Study Center, guanfacine and clonidine improve attention, impulse control and symptoms of tic disorders with children who have both ADHD and tic disorders. Stimulant medications, such as methylphenidate, can exacerbate tic disorders.

    Alternatives

    • Other medications for treating ADHD include amphetamines, methylphenidate and atomoxetine.

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