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Histamine Diseases

Histamine is often associated with allergies when it triggers an inflammatory response to allergens that attack the body. Histamine controls various bodily functions and is also an indicator of some serious diseases.

  1. Histamine

    • Histamine is a biogenic amine which regulates immune responses. It controls the stimulation of gastric secretions and the constriction of bronchial smooth muscle. Histamine is a neurotransmitter that triggers the inflammation response.

    Schizophrenia

    • Histamine is a neurotransmitter in the brain. Levels of histamine in the blood that are either too high or too low have been found to be related to schizophrenia.

    Histamine and Schizophrenia

    • According to an article on The Bio-Communications Research Institute's website, low histamine levels are often associated with paranoia, sleepiness, low libido, easy frustration and tension headaches. High histamine levels are often related to obsession and compulsion, depression, migraine headaches and chronic muscle spasm syndrome.

    Liver Disease

    • Histamine has been found to be elevated in patients with chronic cholestatic liver disease, according to the Journal of Clinical Investigation. This seems to occur because a diseased liver cannot stop the flow of histamine in portal venous blood like a healthy liver does. Elevated histamine is one indicator of liver disease.

    Inflammatory Bowel Disease

    • Histamine mast cells are elevated in patients with inflammatory bowel disease such as colitis and Chron's disease. Histamine is a neurotransmitter which controls the inflammatory response in these diseases. Heightened levels of histamine are indicators of these diseases.

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