Reactions to Gadolinium Dye

Gadolinium dye reactions, while rare, can be life-threatening in some cases. Patients who receive gadolinium dye need to know and watch for signs of reactions to prevent situations of serious reaction from turning fatal.

Identification

• Common reactions to gadolinium dye are skin-related, such as rash, itching, hives, sweating and swelling of the face. Since the dye can irritate the veins into which it is administered, it can also cause inflammation of these veins or even blood clots. Renal failure patients can develop an advanced form of renal failure known as nephrogenic systemic fibrosis/nephrogenic fibrosing dermopathy (NSF/NFD).

Significance

• Doctors and patients should be aware of the signs of an allergic reaction. Any signs the patient has of skin itching, rash, hives or swelling warrant observation and treatment if necessary.

Function

• Gadolinium contrast agent plays an important role in diagnosing and evaluating certain disorders. When used during tests, the dye can assist in determining kidney function, and helps diagnose diseases such as multiple sclerosis. However, patients and doctors must weigh the risks and benefits for the individual before deciding on using a contrast agent.

Considerations

• Patients with kidney problems are an at-risk population for severe problems due to gadolinium dye use.

Warning

• If a patient has a reaction to gadolinium dye, it is necessary to contact a doctor to find out what steps to take. In severe cases of allergic reaction or kidney deterioration, emergency care is the best option to prevent tragedy.