What Is Phosphatidylserine Used for?

Phosphatidylserine is a chemical compound found in the biological membranes of both plants and animals. Also referred to a PS, phosphatidylserine has been used as a dietary supplement since the 1970s as a memory enhancer. PS has generated interest from the medical community as a possible treatment for Alzheimer's disease, dementia and other age-related memory problems. PS has undergone numerous double-blind studies to determine its effectiveness, but there is as yet no definitive consensus on its effectiveness.

Safety

• In a final decision letter from the Office of Nutritional Products, Labeling and Dietary Supplements dated May 13, 2003, the Food and Drug Administration concluded that phosphatidylserine was safe and lawful to use as a dietary supplement, as long as any bovine-derived sources did not come from any country where BSE exists.

Dementia

• Phosphatidylserine is used as a supplement to reduce the risk of dementia in the elderly. In their final decision letter, the FDA concluded there was "little scientific evidence" to support this claim.

Cognitive Dysfunction

• Phosphatidylserine may be used to reduce the risk of cognitive dysfunction in the elderly. In their final decision letter, the FDA concluded there was "little scientific evidence" to support this claim.

Alzheimer's Disease

• Phosphatidylserine may be a potential treatment for Alzheimer's disease. Although numerous studies have indicated an improvement in patient's cognitive abilities, these improvements only remained for a few months and were only observed in less severe cases.

Nervous System

• Phosphatidylserine is frequently touted as a supplement that helps to enhance the function of the nervous system, improve memory and elevate mood.