Caudal Regression What Is

Caudal regression (CR), also known as sacral agenesis, is a neural tube defect that affects the formation of the lower spine and the structures attached to it. This can lead to a range of problems, including incontinence, paralysis, and deformities of the legs and feet.

CR is a relatively rare condition, affecting about 1 in 25,000 babies born in the United States. It is thought to be caused by a combination of genetic and environmental factors, including maternal diabetes, smoking, and alcohol use.

The symptoms of CR can vary depending on the severity of the condition. In some cases, people with CR may have only minor problems, such as difficulty controlling their bladder or bowels. In other cases, people with CR may be paralyzed from the waist down or have severe deformities of the legs and feet.

CR is diagnosed with a combination of prenatal tests and physical exams. Prenatal tests that can be used to diagnose CR include ultrasound and MRI scans. Physical exams can be used to assess the extent of the neural tube defect and to identify any associated problems.

Treatment for CR depends on the severity of the condition. In some cases, treatment may only involve monitoring the child's condition and providing support for the family. In other cases, treatment may involve surgery to correct deformities or to improve function.

The outlook for people with CR varies depending on the severity of the condition. People with mild CR may go on to live full and active lives. People with severe CR may have more challenges, but with early intervention and support, they can still achieve many of their goals.

Here are some additional facts about CR:

* CR is more common in females than in males.

* The risk of CR increases with maternal age.

* CR is often associated with other birth defects, such as heart defects, kidney problems, and cleft lip and palate.

* There is no cure for CR, but there are a variety of treatments that can help to improve the quality of life for people with this condition.