What causes low segmented neutrophils and high lymphocytes?

Causes of low segmented neutrophils and high lymphocytes:

1. Viral infections: The most common cause of low segmented neutrophils and high lymphocytes is a viral infection. When the body is fighting a viral infection, the immune system produces more lymphocytes to help fight off the infection. This can lead to a decrease in the number of segmented neutrophils, which are a type of white blood cell that helps to fight off bacterial infections.

2. Bacterial infections: Some bacterial infections can also cause low segmented neutrophils and high lymphocytes. This is most commonly seen in cases of sepsis, a life-threatening condition that occurs when bacteria enter the bloodstream.

3. Autoimmune diseases: Autoimmune diseases are conditions in which the immune system attacks the body's own tissues. This can lead to a decrease in the number of segmented neutrophils, as well as an increase in the number of lymphocytes. Some autoimmune diseases that can cause these changes include lupus, rheumatoid arthritis, and Crohn's disease.

4. Leukemia: Leukemia is a cancer of the white blood cells. In some cases, leukemia can cause low segmented neutrophils and high lymphocytes.

5. Medications: Some medications can cause low segmented neutrophils and high lymphocytes. This is most commonly seen with chemotherapy drugs, which are used to treat cancer.

6. Bone marrow disorders: Bone marrow disorders can affect the production of white blood cells, including segmented neutrophils and lymphocytes. This can lead to low segmented neutrophils and high lymphocytes. Some bone marrow disorders that can cause these changes include aplastic anemia, myelodysplastic syndrome, and leukemia.