Definition of Lactic Acidosis

Lactic acidosis occurs in the body when lactate and blood pH levels become unbalanced. This condition can be fatal if left untreated as it causes decreased liver functionality.

Cause

• Lactic acidosis can be caused by cancer, kidney disease, respiratory failure or AIDS. This condition can also be brought on by rigorous exercise.

Symptoms

• Patients with lactic acidosis may experience upset stomach, lethargy, trouble breathing, circulation problems in their hands and feet, increased weight loss and tenderness when their liver is touched.

Diagnosis

• Blood tests that evaluate liver function, electrolyte and blood pH levels, and lactate levels will be ordered to confirm a diagnosis of lactic acidosis.

Treatment

• Hospitalization and a respirator may be used to treat severe cases of lactic acidosis. Intravenous fluids may be given, and any medications that are contributing to the lactic acidosis will be temporarily discontinued.

Risk Factors

• Patients that are overweight or are HIV positive and taking medication for a hepatitis-C infection are at increased risk for developing lactic acidosis. Women are also more susceptible to this condition as are diabetics who take certain medications to manage their diabetes.