Brittle Bone What Is

Brittle bone disease, also called osteogenesis imperfecta (OI), is a group of genetic conditions that cause bones to break easily. Babies born with OI may have soft, weak bones that deform easily. Infants and children with OI often have delayed motor skills and may have short stature.

Some signs of brittle bone disease may include:

- Fragile bones that fracture easily, often after little or no trauma

- Deformities of the legs and arms

- Bone pain

- Muscle weakness

- Short stature

- Curved spine (scoliosis)

- Respiratory problems

- Hearing loss

- Vision problems

- Skin that bruises easily

- Loose joints

- Blue sclerae (the white part of the eye)

Treatment for brittle bone disease may include:

- Medications to strengthen bones and reduce bone fractures

- Physical therapy to help improve muscle strength and flexibility

- Occupational therapy to help the person develop skills for everyday activities

- Surgery to correct deformities and to stabilize fractures

- Bracing to help support bones and prevent fractures

The severity of brittle bone disease varies from person to person. Some people may have only mild symptoms, while others may have severe deformities and disabilities. There is no cure for brittle bone disease, but treatment can help to improve the quality of life for people with the condition.