Bisphosphate Joint Pain

Bisphosphonates are a class of drugs used most frequently to treat bone loss and osteoporosis. The drug was discovered in the 19th century, but was not used for the treatment of bone loss until 1960. Myriad side effects have been reported including joint pain.

Benefits

• Bisphosphonates are beneficial to men and women at risk for bone fractures and breaks. They are used to treat osteoporosis and are effective.

Significance

• Increased bone density, strength, and formation has been observed by those taking bisphosphonates. Long term results and side effects are still undetermined.

Considerations

• Bisphosphonates are not absorbed well when food in present in the stomach. In order to prevent irritation to the esophagus, bisphosphonates must be taken with a full glass of water (at least 4 ounces).

Effects

• Numerous side effects have been reported and joint pain is one of them. A January 7, 2008 article published at Medical News Today reported that the FDA warned doctors of the link between joint pain and bisphosphonates. Not all patients are affected with joint pain. The pain is relieved gradually and often immediately when the drug is discontinued.

Warning

• The January 2008 report addressed the possibility of patients using bisphosphonates experiencing incapacitating bone, jaw, muscle, and joint pain.

Time Frame

• Those patients who experience joint pain can do so after just a few days or dosages. Others may feel pain within months, and some may not have pain until years after.