Where does ether exert its effects on nerve activity?

Ether exerts its effects on nerve activity primarily at the site of the neurotransmitter-gated ion channels, which are responsible for the rapid excitability of the nerve cells. Specifically, ether acts on the gamma-aminobutyric acid (GABA) receptors, causing an increase in the inhibitory chloride ion influx. This leads to hyperpolarization or less excitable nerve cells, resulting in the sedative and anesthetic effects of ether. These changes can modify the signal transmission dynamics across neuronal networks, leading to the characteristic alterations in consciousness, perception, movement, and sensation during ether anesthesia.