Methyl B12 Vs. Cyanocobalamin B12

Vitamin B12 is one of a group of compounds called cobalamins. The structure of cobalamins is closely related to hemoglobin in the blood. Lack of cobalamins can cause anemia and traditionally form a part of anemia treatment. For many years cyancobalamin was the only form of B12 available until methylcobalamin was discovered in the 1990s.

Cyancobalamin

• This form of B12 boosts energy levels and improves metabolic function. It is also plays a part in acetycholine production, a neurotransmitter that is involved in the memory and learning roles. Additionally, in combination with B6 and folic acid, it produces homocysteine to protect the heart. It is a useful supplement to a vegetarian diet.

Methylcobalamin

• Methylcobalamin is predominantly, but not exclusively, associated with treating neurological disorders. It is considered beneficial for Parkinson's and Alzheimer's as well as chronic fatigue syndrome. A clinical study in "The Journal of Internal Medicine" shows it is valuable in alleviating some multiple sclerosis symptoms.

Considerations

• Cyancobalamin is a cheaper and widely available form of B12. However, the liver has to convert cyancobalamin into methylcobalamin before the body can use it. Products that are primarily methylcobalamin become active quicker so are thought to be more effective.