How Are Dilantin Levels Measured?

Dilantin, or phenytoin, is one of the most widely prescribed anticonvulsants used to control seizure disorders. It is important for the correct Dilantin levels to be maintained in each person or seizures may occur. Dilantin levels in the body are measured through blood tests to ensure an effective dosage is being administered.

Clinically Effective Levels

• The clinically effective level of Dilantin in the body is between 10 and 20 micrograms per milliliter, or mcg/ml. Individuals need to be taking a set dose for seven to ten days in order for a blood test to accurately show the blood levels of Dilantin the current dosage is producing. Individuals with epilepsy or other seizure disorders may be on Dilantin for a lifetime, so periodic blood tests are needed to help make dosage adjustments as necessary.

Dosages

• Dosages of Dilantin are dependent upon several different factors. Doses will start out low for those just starting the drug and will be increased slowly until the correct blood levels are measured. Dosages depend on what form of Dilantin a person is taking, how many times a day it is being taken and if other seizure medications are being used.

Side Effects

• As with all drugs, there are many potential side effects associated with Dilantin. Sleep disturbances, changes in mood, decreased muscle control and coordination, shakiness and slurred speech commonly occur in patients taking Dilantin. Good dental care is critical in those using the drug as sensitivity of the gums can be greatly heightened. Other anticonvulsant medications can be tried if the side effects experienced with Dilantin are too severe. However, it is important to speak with your physician about concerns regarding side effects and to never discontinue the use of Dilantin without a physician's approval and supervision.

Other Drugs and Supplements

• Using Dilantin in combination with other medications, vitamins and supplements may impact the efficacy of the drug. Consult your physician before taking any additional medications or supplements to ensure they will not interfere with maintaining effective Dilantin levels within the body. Dilantin dosages may need to be adjusted under a physician's supervision with addition or removal of any medications from a regular regimen.

Discontinuation

• Some children and adults who once needed medication to control their seizures may be able to live seizure-free after stabilizing while on medications such as Dilantin. Individuals should never terminate an anticonvulsant regimen on their own; rather, it should be done under medical supervision. If a physician feels that a seizure disorder has stabilized, he or she may create a plan to slowly wean a patient off of a Dilantin regimen, careful to watch for signs or changes that may indicate the return of the seizures and need to reinstate effective levels of the drug.