Side Effect of Stopping Depakote

An oral drug used to treat epilepsy, bipolar disorder and headaches, Depakote works by restoring balance to certain substances within the brain. There are side effects when taking the drug, as well as one particular effect when stopping the drug too quickly. To ensure a lack of seizures when ceasing the use of Depakote, be sure to withdraw slowly and follow doctor's orders.
  1. Background

    • Available in the United States since 1983, Depakote is an oral drug used to restore the balance of certain natural substances in the brain.

    Uses

    • Depakote is prescribed to treat epilepsy, bipolar disorders and migraine headaches.

    Interactions

    • Taking Depakote with drugs such as Thorazine and Tagamet may raise Depakote levels in the body. Taking with drugs such as Valium and Coumadin could increase the levels of these drugs in the body.

    Seizures

    • Stopping Depakote too quickly may result in a return of seizures.

    Ceasing

    • According to Dr. Roger Gould, when stopping Depakote do so slowly and ask your doctor if you should substitute an alternative medication.

    Warnings

    • Depakote should not be used by pregnant women as it could cause birth defects, or by persons with liver disease or urea cycle disorder.

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