What research has been done on buchu?

Pharmacology

Buchu has antibacterial, antiviral, diuretic, anti-inflammatory, and antispasmodic properties. It has been used traditionally for the treatment of urinary tract infections, kidney stones, and rheumatism.

Preclinical studies

In vitro studies have shown that buchu extracts have antibacterial activity against a variety of Gram-positive and Gram-negative bacteria, including Escherichia coli, Staphylococcus aureus, and Pseudomonas aeruginosa. Buchu extracts have also been shown to inhibit the growth of fungi, such as Candida albicans.

Inflammation

A study in rats found that buchu extract reduced inflammation in the paw induced by carrageenan. Buchu extract also inhibited the production of inflammatory cytokines, such as tumor necrosis factor-alpha (TNF-alpha) and interleukin-1 beta (IL-1 beta).

Urinary tract health

A study in rats found that buchu extract reduced the formation of kidney stones. Buchu extract also increased the flow of urine and reduced the levels of calcium and oxalate in the urine.

Clinical studies

A clinical study in humans found that buchu extract was effective in treating urinary tract infections. Buchu extract was also found to be safe and well-tolerated.

Other studies

Buchu has also been shown to have antioxidant and free radical scavenging activities. Buchu extracts have also been shown to inhibit the growth of cancer cells.

Conclusion

Buchu is a promising natural product with a variety of pharmacological activities. Further clinical studies are needed to confirm the efficacy and safety of buchu for the treatment of various health conditions.