How does angina affect a tissue?

Angina, also known as angina pectoris, is a symptom of coronary artery disease characterized by chest pain or discomfort that occurs when the heart muscle does not get enough oxygen-rich blood. This lack of blood flow can affect tissues by causing:

1. Ischemia: Angina is primarily caused by a temporary reduction in blood flow (ischemia) to the heart muscle. When the heart muscle does not receive enough oxygen-rich blood, it can lead to ischemia and chest pain.

2. Pain: The pain or discomfort associated with angina is typically felt in the center or left side of the chest. It may also be experienced in other areas, such as the shoulders, arms, neck, jaw, or back.

3. Shortness of Breath: Angina can cause shortness of breath or tightness in the chest. This occurs because the heart is not able to pump enough oxygenated blood to meet the body's demands, leading to a feeling of breathlessness.

4. Fatigue and Weakness: Reduced blood flow to the heart can also result in fatigue and weakness. This is because the heart muscle is unable to work efficiently due to the lack of oxygen and nutrients.

5. Nausea and Sweating: Angina may be accompanied by nausea, vomiting, or excessive sweating. These symptoms can occur due to the activation of the sympathetic nervous system, which is part of the body's response to stress and decreased oxygen supply.

It's important to note that the severity of symptoms and the tissues affected by angina can vary from person to person and may also depend on the underlying cause and extent of coronary artery disease.