Pentoxifylline Uses

Pentoxifylline, marketed under the name Trental by the pharmaceutical company Sanofi-Aventis, is a veterinary drug available only by prescription to treat skin diseases and circulation problems. While a generic version exists, comparative studies have not been done between the Trental and the generic, according to a June, 2007, article in Veterinary Medicine. It's used to treatment a variety of canine ailments and should not be given to pregnant or lactating dogs.
  1. Atopic Canine Dermatitis

    • Numerous conditions cause incessant scratching in dogs. One common culprit is atopic canine dermatitis. Dogs with this problem generally exhibit signs by their first birthday. Initially, it may be more severe in warm weather, as allergens such as plant pollen proliferate. The feet, ears and muzzle may be particularly affected. Diagnosis by testing rules out similar skin conditions, such as sarcoptic mange. Skin tests must be done to discover which allergens are responsible for the dermatitis. Pentoxifylline is one of several medications used to alleviate inflammation, along with dietary changes if food allergies are involved. While atopic canine dermatitis can't be cured, the disease is manageable.

    Shock

    • Dogs going into shock, whatever the reason, will not have enough blood circulating through their system. Pentoxifylline, which improves blood flow, is used for dogs suffering from hemorrhagic shock, resulting from serious blood loss. Being attacked by another dog, hit by a car, or other accidents are the primary causes of hemorrhagic shock. As it is an emergency situation, get the dog to the vet immediately for treatment. Try to keep the animal warm en route to the veterinary hospital.

    Thrombosis

    • Because it increases blood flow, Pentoxifylline is used in cases of thrombosis, or blood clots in blood vessels. Although the condition can be fatal, early diagnosis allows treatment of the thrombosis with blood-thinning agents along with pain medication and intravenous fluids. Thrombosis usually comes on suddenly, and time is of the essence to save the pet. Take your dog to the vet immediately if he has difficulty breathing, suffers sudden limb impairment, loses consciousness, or exhibits neurological abnormalities.

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