What could cause chills if no infection?

There are several potential causes of chills in the absence of an infection. Here are a few possibilities:

1. Hypothermia: When your body temperature drops significantly below normal, you may experience chills as your body tries to conserve heat.

2. Certain Medications: Some medications, such as chemotherapy drugs, can cause chills as a side effect.

3. Autoimmune Disorders: Some autoimmune conditions, such as lupus or rheumatoid arthritis, can lead to inflammation and chills.

4. Hypoglycemia: Low blood sugar levels can sometimes trigger chills.

5. Anxiety or Emotional Stress: In some individuals, intense anxiety or emotional stress can manifest with physical symptoms, including chills.

6. Hormonal Changes: Hormonal fluctuations, such as those experienced during menopause, can cause chills.

7. Cirrhosis: Advanced liver disease known as cirrhosis can lead to chills and other symptoms.

8. Cancer: In rare cases, chills may be an early sign of certain cancers, especially if accompanied by other symptoms.

9. Allergic Reactions: Severe allergic reactions, also known as anaphylaxis, can cause chills along with other symptoms.

10. Drug Withdrawal: Abruptly stopping certain medications, such as alcohol or sedatives, can cause chills and withdrawal symptoms.

11. Kidney Stones: Severe kidney stones can occasionally trigger chills and discomfort.

It's important to note that chills alone are not a specific indicator of any particular condition and can have various underlying causes. If you experience chills without an apparent infection and they persist or are accompanied by other concerning symptoms, it is advisable to consult a healthcare professional for proper evaluation and diagnosis.